查高峰,博士,讲师/硕士生导师
地址:中国.湖北.武汉.东湖新技术开发区光谷一路206号,
信誉最好的网投平台
邮编:430205
Email:zgflmx@wit.edu.cn; zgflmx@whut.edu.cn
电话:+86-27-87194980
2018.09 至今 卡罗琳斯卡医学院(Karolinska Institutet),博士后;
2015.09 - 2018.06 博士,材料科学与工程专业,武汉理工大学,导师:秦华利教授;
2013.09 - 2015.06 硕士,药学专业,化学化工与生命科学学院,武汉理工大学;
2003.09 - 2007.06 本科,制药工程专业,化学工程学院,武汉理工大学
2018.07 至今 信誉最好的网投平台,讲师
2007.07 – 2013.05 历任药物合成技术员、中试车间工艺员、中试车间主任,东阳光药业
第二代点击化学-六价硫氟交换化学(Sulfur(VI) Fluoride Exchange, SuFEx)
六价硫氟交换化学在化学生物学上的应用(Application of SuFEx in chemical biology)
抗肿瘤药物的设计与开发(Design and development of anti-cancer drugs)
代表性论文(专利,专著):
1. G.-F. Zha#, Q. Zheng#, J. Leng, P. Wu, H.-L. Qin*, K. B. Sharpless*, Palladium-Catalyzed Fluorosulfonylvinylation of Organic Iodides, Angew. Chem. Int. Ed. 2017, 56, 4849-4852. (Co-first author, JCR1区,top期刊,IF:12.10).
2. G.-F. Zha#, W.-Y. Fang#, Y.-G. Li, J. Leng, X. Chen, H.-L. Qin*, SO2F2 Mediated Oxidative Dehydrogenation and Dehydration of Alcohols to Alkynes, J. Am. Chem. Soc. 2018, 140, 17666-17673. (Co-first author, JCR1区, top期刊,IF:14.35)
3. G.-F. Zha#,S.-M. Wang#, K. P. Rakesh*, S. N. A. Bukhari, H. M. Manukumar, H. K. Vivek, N. Mallesh, H.-L. Qin*, Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug resistance of bacterial infections, Eur. J. Med. Chem. 2019, 162, 364-377. (Co-first author, JCR1区, top期刊,IF: 4.82)
4. G.-F. Zha,K. P. Rakesh*, H. M. Manukumar, C. S. Shantharam, S. Long*, Pharmaceutical significance of azepane based motifs for drug discovery: A critical review, Eur. J. Med. Chem., 2019, 162, 465-494. (JCR1区, top期刊,IF: 4.82)
5. G.-F. Zha#, W.-Y. Fang#, J. Leng, H.-L. Qin*, Simple, Mild and Robust Oxidation of Alcohols to Aldehydes or Ketones Using DMSO as Solvent and Oxidant Mediated by SO2F2/K2CO3, Adv. Synth. Catal. DOI: 10.1002/adsc.201900104. (Co-first author, JCR1区,top期刊,IF: 5.12)
6. G.-F. Zha, H.-L. Qin*, B. G. M. Youssif, M. W. Amjad, M. A. G. Raja, A. H. Abdelazeem, S. N. A. Bukhari*, Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance, Eur. J. Med. Chem. 2017, 135, 34-48. (JCR1区, top期刊,IF: 4.82)
7. G.-F. Zha, G. A. L. Bare, J. Leng, Z.-P. Shang, Z. Luo, H.-L. Qin*, Gram-scale synthesis of β-(Hetero)arylethenesulfonyl fluorides via a Pd(OAc)2(cat.)/DDQ or AgNO3 mediated oxidative Heck process, Adv. Synth. Catal. 2017, 359, 2137-3242. (JCR1区,top期刊,IF: 5.12)
8. X. Chen#, G.-F. Zha#, G. A. L. Bare#, J. Leng, S.-M. Wang, H.-L. Qin*, Synthesis of a class of fused δ-sultone heterocycles via DBU-catalyzed direct annulative SuFEx Click of ethenesulfonyl fluorides and pyrazolones or 1,3-dicarbonyl compounds, Adv. Synth. Catal. 2017,359, 3254-3260.(Co-first author, JCR1区,top期刊,IF: 5.12)
9. G.-F. Zha, J.-B. Han, X.-Q. Hu, H.-L. Qin*, W.-Y. Fang, C.-P. Zhang*, Silver-mediated direct trifluoromethoxylation of α-diazo esters via the-OCF3 anion, Chem. Commun., 2016, 52(47), 7458-7461. (JCR1区,top期刊,IF: 6.29)
10. G.-F. Zha, H.-L. Qin*, E. A. B. Kantchev*, Cooperativity of axial and centre chirality in the biaryl disulfoxide/Rh(I)-catalysed asymmetric 1,4-addition of arylboronic aids to 2-cyclohexenone: a DFT study, Org. Biomol. Chem., 2017, 15(10), 2226-2233. (JCR1区, IF:3.42)
获奖情况
2008 宜都市科技进步一等奖,第一完成人,宜都市人民政府
2016-2018 博士研究生卓越奖学金(3.6万/年),武汉理工大学
2017 博士研究生国家奖学金